Functional Lab Testing

GI-MAP Explained

August 29, 20254 min read

GI-MAP Explained: What It Shows, When It’s Worth It, and What to Do Next

Stop guessing. Use data to make a plan.

The GI-MAP is a DNA (qPCR) stool test that screens for pathogens, microbiome balance, digestion/immune markers and gut inflammation. It’s worth it when symptoms persist (IBS, bloating, reflux, skin/hormones/energy issues) and you need clarity to build a targeted protocol. Prepare properly, act on the results in a structured 6-step plan, and re-test only when needed.


What is the GI-MAP?

The GI-MAP (Gastrointestinal Microbial Assay Plus) is a laboratory stool DNA test that uses qPCR to quantify microbes and gut-related markers. It helps identify root-cause patterns behind digestive symptoms and systemic complaints.

What it commonly measures

  • Pathogens & overgrowths: bacteria, parasites and certain viruses

  • H. pylori (with virulence factors)

  • Commensal bacteria (beneficial/keystone species) and opportunistic/dysbiotic bacteria

  • Yeast/fungi (e.g., Candida)

  • Immune & inflammation markers: e.g., secretory IgA, calprotectin

  • Digestion/absorption markers: e.g., elastase, occult blood, fat malabsorption

  • Detox/estrogen-related enzymes: e.g., β-glucuronidase

Reality check: No single stool test “diagnoses” everything. We interpret results in context with symptoms, history and (if available) standard bloodwork.


When is the GI-MAP worth it?

Choose it when one or more apply:

  • Chronic gut symptoms: IBS, bloating, reflux, irregular stools, post-infection issues

  • Skin & immune: acne/rosacea, eczema, recurrent infections, auto-immune history

  • Hormones & mood: perimenopause/menopause symptoms, thyroid concerns, anxiety/low mood

  • Energy & weight: fatigue, brain fog, stubborn weight/inflammation despite “doing everything right”

  • You’ve tried generic protocols with little change and want targeted next steps

When it’s not the first step

  • Red-flag symptoms → see your doctor first: unexplained weight loss, blood in stool, fever, persistent night sweats, severe pain, iron-deficiency anemia.

  • SIBO suspicion → breath testing is primary; GI-MAP can still inform the broader picture but does not diagnose SIBO.


How to prepare (follow your kit’s instructions)

  • Keep your usual diet in the week before collection (unless told otherwise).

  • Typically wait ~4 weeks after antibiotics, and pause antimicrobials/herbal protocols for ~2 weeks.

  • Many labs advise pausing probiotics for 1–2 weeks.

  • Avoid sample contamination; collect on a “normal” day (not during acute gastroenteritis).

(Always follow the exact prep sheet in your kit.)


How I interpret a GI-MAP (the framework)

  1. Symptoms first: what you feel, when it started, what helps/worsens

  2. Rule-outs: red flags, need for referral, relevant bloodwork

  3. Prioritize findings: pathogen/overgrowth → inflammation → digestion → immune tone → microbiome resilience

  4. Build the plan: minimum effective steps, clear timelines and checkpoints


What to do next: a 6-step action plan

  1. Stabilize foundations (Weeks 1–2)
    Sleep, protein & fiber targets, blood-sugar rhythm, hydration, gentle movement.

  2. Targeted “clear” phase (Weeks 2–6)
    If indicated: doctor-prescribed meds or evidence-based botanicals against priority organisms. Avoid “kitchen-sink” protocols.

  3. Support digestion
    Stomach acid support if needed, digestive enzymes, bile support for fat malabsorption, regular mealtimes.

  4. Soothe & repair the gut lining
    L-glutamine, zinc carnosine, demulcents (e.g., DGL), omega-3, polyphenols as appropriate.

  5. Rebuild the microbiome
    Strain-specific probiotics and prebiotic fibers tailored to findings (titrate slowly).

  6. Retest or reassess (Week 8–12+)
    Retest only if results would change the plan; otherwise track symptoms, stool form, energy, sleep, skin and objective markers.

Important: Treat the person, not just the paper. We don’t chase every microbe; we address the highest-leverage findings.


Common myths & mistakes

  • “A single bad bug is the whole story.” Often it’s a pattern, not one culprit.

  • “High/low = always treat.” Context matters; some shifts are transient.

  • “Everyone needs the same cleanse.” No. Personalization prevents relapse.

  • “More supplements = faster results.” Minimum effective dose wins.


Costs & practicalities

  • The test kit is billed separately from consultations.

  • Analysis of one test is included in my Comprehensive Program.

  • In-person appointments include the blood draw (if needed for standard labs).

  • Results typically return in 2–3 weeks.


Where GI-MAP fits with other testing

  • Pairs well with: bloodwork (iron, thyroid, inflammation, lipids), DUTCH for hormones, Organic Acids for metabolic clues.

  • Choose the fewest tests that answer your clinical question.


Work with me (online or in person)

I help clients worldwide via secure video, and in person in the Málaga area (Spain) and during set periods in Denmark.

Not sure if GI-MAP is right for you? Book a free 15-minute call to find your best next step.


FAQ

Is GI-MAP a diagnosis?
No. It’s a data point. We combine it with symptoms, history and, when needed, medical evaluation.

Do I need to retest?
Only if a new result would change the next step. Many clients don’t need it once symptoms and markers normalize.

Can you work with my doctor?
Yes. I can provide a concise summary to share and coordinate care.

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